Author

M. Charnley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. H. Allam· 2 shared J. Ratcliffe· 2 shared K. Pham· 2 shared N. P. Reynolds· 2 shared S. M. Russell· 2 shared B. Abbey· 1 shared C. J. H. Chong· 1 shared C. Johnson· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

A. H. Allam

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Extensive collagen deposition by mesenchymal stem cells cultured in 3D self-assembled peptide scaffolds as revealed by nanoplasmonic colorimetric histology.

C. J. H. Chong, V. Lim, M. Charnley, J. Ratcliffe, E. Field, L. M. Caballero-Aguilar, C. Johnson, J. Orian, K. Caracciolo, E. Balaur, B. Abbey, S. E. Moulton, K. J. Binger, N. P. Reynolds

The paper investigates collagen deposition by mesenchymal stem cells in 3D peptide scaffolds and introduces a label-free method to image collagen.

bioRxiv · Sep 15, 2022 · PreprintBioengineering

E-cadherin in developing murine T cells controls spindle alignment and differentiation during β-selection

M. Charnley, A. H. Allam, L. M. Newton, P. O. Humbert, S. M. Russell

This study shows E-cadherin in murine T cells helps align the mitotic spindle and supports differentiation during β-selection by influencing immunological synapse formation.

bioRxiv · Jun 14, 2022 · PreprintCell Biology

Neurotoxic Amyloidogenic Peptides Identified in the Proteome of SARS-COV2: Potential Implications for Neurological Symptoms in COVID-19

S. Islam, M. Charnley, G. Bindra, J. Ratcliffe, J. Zhou, R. Mezzenga, M. D. Hulett, K. Han, J. T. Berryman, N. P. Reynolds

The paper identifies amyloidogenic peptides in SARS-CoV-2 that are toxic to neuronal cells, suggesting they may contribute to neurological symptoms and long COVID.

bioRxiv · Nov 24, 2021 · PreprintBiochemistry

Developing T cells form an immunological synapse for passage through the β-selection checkpoint

A. H. Allam, M. Charnley, K. Pham, S. Russell

The paper shows developing T cells form an immunological synapse to pass the β-selection checkpoint, integrating signals from Notch, CXCR4, and MHC.

bioRxiv · Aug 12, 2019Immunology

A new role for Notch in control of polarity and asymmetric cell division of developing T cells

M. Charnley, M. Ludford-Menting, K. Pham, S. M. Russell

This study shows Notch signaling directly controls asymmetric cell division in developing T cells by regulating Notch1 and fate determinants distribution.

bioRxiv · Jun 14, 2019Cell Biology