Chromatinization Modulates Topoisomerase II Processivity
J. Lee, M. Wu, J. Inman, G. Singh, S. h. Park, J. H. Lee, R. M. Fulbright, Y. Hong, J. D. Jeong, J. M. Berger, M. D. Wang
This study shows that chromatin enhances topoisomerase II processivity under both high and low torsional stress, with topo II relaxing over 6000 DNA turns on plectonemic DNA.
bioRxiv · Oct 3, 2023Biophysics