De novo design of modular peptide binding proteins by superhelical matching
K. Wu, H. Bai, Y.-T. Chang, R. Redler, K. E. McNally, W. Sheffler, T. Brunette, D. R. Hicks, T. E. Morgan, T. J. Stevens, A. Broerman, I. Goreshnik, M. DeWitt, C. M. Chow, Y. Shen, , D. Baker
This paper introduces a method to design modular peptide binding proteins that bind repeating peptide sequences with high specificity and affinity.
bioRxiv · Nov 14, 2022 · PreprintBiochemistry