Author

M. Dottori

Primary ORCID profile (0000-0002-9975-0367 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

M. DottoriiD1 paper · Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini"

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

S. Maksour· 2 shared A. Hulme· 1 shared A. J. Hulme· 1 shared C. Turner· 1 shared G. O'Neill· 1 shared H. Targa Dias Anastacio· 1 shared K. Sidhu· 1 shared L. Lisowski· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

S. Maksour

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2 papers

Recent·Most cited

Alzheimer's disease induced neurons bearing PSEN1 mutations exhibit reduced excitability

S. Maksour, R. K. Finol-Urdaneta, A. J. Hulme, M. C. Cabral-da-Silva, H. Targa Dias Anastacio, R. Balez, T. Berg, C. Turner, S. Sanz Munoz, M. Engel, P. Kalajdzic, L. Lisowski, K. Sidhu, P. S. Sachdev, M. Dottori, L. Ooi

This study investigates how PSEN1 mutations in Alzheimer's disease affect neuronal excitability using iPSC-derived neurons and finds reduced excitability and altered Kv/Nav channel currents in mutant neurons.

bioRxiv · Mar 22, 2024 · PreprintCell Biology

Parsing the effect of co-culture with brain organoids on Diffuse Intrinsic Pontine Glioma (DIPG) using quantitative proteomics

V. Prior, S. Maksour, S. Miellet, A. Hulme, Y. Chen, M. Mirzaei, Y. Wang, M. Dottori, G. O'Neill

The paper uses proteomics to compare DIPG cells in co-culture with brain organoids to control conditions, finding changes in adhesion, DNA synthesis, and dendrite growth pathways.

bioRxiv · May 19, 2023Cancer Biology