Author

L. Lisowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Westhaus· 2 shared I. E. Alexander· 2 shared M. Cabanes-Creus· 2 shared A. Affes· 1 shared A. B. Lyons· 1 shared A. Braun· 1 shared A. Ehrhardt· 1 shared A. F. Sharland· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersBioengineering

A. Westhaus

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Alzheimer's disease induced neurons bearing PSEN1 mutations exhibit reduced excitability

S. Maksour, R. K. Finol-Urdaneta, A. J. Hulme, M. C. Cabral-da-Silva, H. Targa Dias Anastacio, R. Balez, T. Berg, C. Turner, S. Sanz Munoz, M. Engel, P. Kalajdzic, L. Lisowski, K. Sidhu, P. S. Sachdev, M. Dottori, L. Ooi

This study investigates how PSEN1 mutations in Alzheimer's disease affect neuronal excitability using iPSC-derived neurons and finds reduced excitability and altered Kv/Nav channel currents in mutant neurons.

bioRxiv · Mar 22, 2024 · PreprintCell Biology

ADEVO: Proof-of-concept of Adenovirus Directed EVOlution by random peptide display on the fiber knob

E. Sallard, J. Fischer, N. Beaude, A. Affes, E. Ehrke-Schulz, W. Zhang, A. Westhaus, M. Cabanes-Creus, L. Lisowski, Z. Ruszics, A. Ehrhardt

ADEVO demonstrates a method to generate high-complexity adenovirus libraries for retargeting, showing improved replication and lysis in tumor cells.

bioRxiv · Nov 16, 2023Bioengineering

Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors

A. Westhaus, M. Cabanes-Creus, K. L. Dilworth, E. Zhu, D. Salas Gomez, R. G. Navarro, A. K. Amaya, S. Scott, M. Kwiatek, A. L. McCorkindale, T. E. Hayman, S. Frahm, D. P. Perocheau, B. M. Tran, E. Vincan, , L. Lisowski

This study evaluates six AAV vectors in twelve preclinical liver models to identify the most predictive for AAV capsid selection in human hepatocyte transgene delivery.

bioRxiv · Sep 28, 2022 · PreprintBioengineering

A human adenovirus encoding IFN-γ can transduce Tasmanian devil facial tumour cells and upregulate MHC-I

A. N. Kayigwe, J. M. Darby, A. B. Lyons, A. L. Patchett, L. Lisowski, G.-S. Liu, A. S. Flies

This study shows a human adenovirus encoding IFN-γ can upregulate MHC-I in Tasmanian devil tumor cells, suggesting its potential as a vaccine platform.

bioRxiv · May 29, 2022Immunology

The self-peptide repertoire plays a critical role in transplant tolerance induction

E. T. Son, P. Faridi, M. Paul-Heng, M. Leong, K. English, S. H. Ramarathinam, A. Braun, N. Dudek, I. E. Alexander, L. Lisowski, P. Bertolino, D. Bowen, A. W. Purcell, N. Mifsud, A. F. Sharland

This study identifies immunogenic MHC I peptides involved in transplant tolerance by combining genetic engineering, immunopeptidomics, and T cell analysis.

bioRxiv · Nov 9, 2020Immunology