BiophysicsbioRxiv
Dwarf open reading frame (DWORF) peptide is a direct activator of the sarcoplasmic reticulum calcium pump SERCA.
M. E. Fisher, E. Bovo, E. E. Cho…·H. S. Young
This paper identifies DWORF as a direct activator of SERCA, increasing its turnover rate and calcium reuptake, contrasting with the inhibitory effect of phospholamban.
DOI 10.7554/elife.65545