Author

M. P. Dalton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. V. Zima· 1 shared E. Bovo· 1 shared E. E. Cho· 1 shared H. S. Young· 1 shared I. Bahar· 1 shared J. A. Coleman· 1 shared L. M. Espinoza-Fonseca· 1 shared M. E. Fisher· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiophysics

A. V. Zima

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 5, 2023

Structural mechanisms for VMAT2 inhibition by tetrabenazine

M. P. Dalton, M. H. Cheng, I. Bahar, J. A. Coleman

This study reports the cryo-EM structure of VMAT2 bound to tetrabenazine, revealing its inhibition mechanism and conformational dynamics.

DOI 10.1101/2023.09.05.556211

cryo-EMexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivOct 1, 2020

Dwarf open reading frame (DWORF) peptide is a direct activator of the sarcoplasmic reticulum calcium pump SERCA.

M. E. Fisher, E. Bovo, E. E. Cho…·H. S. Young

This paper identifies DWORF as a direct activator of SERCA, increasing its turnover rate and calcium reuptake, contrasting with the inhibitory effect of phospholamban.

DOI 10.7554/elife.65545

biophysical modelingexperimental assay

𝕏 PostBluesky