BiophysicsbioRxiv
Protein structural transitions critically transform the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it
A. R. Tejedor, I. Sanchez-Burgos, M. Estevez-Espinosa…·J. R. Espinosa
The paper shows that inter-protein β-sheets increase RNA-binding protein condensate viscosity and alter network connectivity, leading to gelation, but RNA can slow this process.
DOI 10.1038/s41467-022-32874-0