Author

M. F. Leite

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

B. E. Ehrlich· 2 shared E. Kruglov· 2 shared N. Ogino· 2 shared A. B. Justino· 1 shared A. Bucksch· 1 shared A. C. M. L. Filho· 1 shared A. Cabral· 1 shared A. Franca· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

B. E. Ehrlich

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Adaptation to volumetric compression drives hepatoblastoma cells to an apoptosis-resistant and invasive phenotype

X. Gong, N. Ogino, M. F. Leite, Z. Chen, R. Liu, E. Kruglov, K. Flores, A. Cabral, G. M. M. Mendes, B. E. Ehrlich, M. Mak

This study shows that volumetric compression in liver cancer cells leads to transcriptional reprogramming, increased invasiveness, and chemoresistance, with potential reversal via calcium signaling.

bioRxiv · Oct 8, 2023 · PreprintCancer Biology

The soil microbiome reduces Striga infection of sorghum by modulation of host-derived signaling molecules and root development

D. Kawa, B. Thiombiano, M. Shimels, T. Taylor, A. Walmsley, H. E. Vahldick, M. F. Leite, Z. Musa, A. Bucksch, F. Dini-Andreote, A. J. Chen, J. Daksa, D. Etalo, T. Tessema, E. E. Kuramae, , S. M. Brady

This study shows that the soil microbiome reduces Striga infection in sorghum by inducing root suberization, aerenchyma formation, and degrading haustorium-inducing factors.

bioRxiv · Nov 6, 2022 · PreprintPlant Biology

Neutrophils regulate ITPR2 levels in epithelia by direct injection of elastase

N. Ogino, M. F. Leite, E. Kruglov, H. Asashima, D. A. Hafler, B. E. Ehrlich, M. Nathanson

The paper shows neutrophils inject elastase into hepatocytes, reducing ITPR2 levels and calcium signals without damaging cells, and identifies a compensatory response in liver biopsies.

bioRxiv · Sep 13, 2022 · PreprintCell Biology

Alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel inhibits proliferation and migration of human liver cancer HepG2 cells

A. B. Justino, R. M. Florentino, A. Franca, A. C. M. L. Filho, R. R. Franco, A. L. Saraiva, M. C. Fonseca, M. F. Leite, F. Salmen Espindola

This study identifies an alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel that inhibits HepG2 cell proliferation and migration by modulating PCNA, EGFR, and intracellular calcium.

bioRxiv · Apr 7, 2021Biochemistry