Cell states beyond transcriptomics: integrating structural organization and gene expression in hiPSC-derived cardiomyocytes
K. A. Gerbin, T. Grancharova, R. Donovan-Maiye, M. C. Hendershott, J. Brown, S. Q. Dinh, J. L. Gehring, M. Hirano, G. R. Johnson, A. Nath, A. Nelson, C. M. Roco, A. B. Rosenberg, M. F. Sluzewski, M. P. Viana, , R. N. Gunawardane
The paper integrates gene expression and sarcomere organization in hiPSC-derived cardiomyocytes to predict subcellular states and reveal correlations between transcript abundance and structural patterns.
bioRxiv · May 26, 2020Cell Biology