G. Seelig

A nanopore interface for high bandwidth DNA computing

This paper introduces a nanopore-based readout method for DNA strand displacement circuits, achieving higher output bandwidth than fluorescence spectroscopy for molecular diagnostics.

A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes

The paper analyzes gene expression changes in hiPSC-derived cardiomyocytes using single-cell RNA-seq, identifying key genes that mark differentiation stages and sources of variation across protocols and cell lines.

Cell states beyond transcriptomics: integrating structural organization and gene expression in hiPSC-derived cardiomyocytes

The paper integrates gene expression and sarcomere organization in hiPSC-derived cardiomyocytes to predict subcellular states and reveal correlations between transcript abundance and structural patterns.

Content-Based Similarity Search in Large-Scale DNA Data Storage Systems

The paper demonstrates content-based image similarity search using a database of 1.6 million images encoded in synthetic DNA, achieving retrieval rates greater than chance.

Microbial single-cell RNA sequencing by split-pool barcoding

The paper introduces microSPLiT, a scRNA-seq method for bacteria, and applies it to Bacillus subtilis to reveal transcriptional states and novel gene expression patterns.

Enzyme-Free Nucleic Acid Dynamical Systems

The paper demonstrates that DNA-based molecular systems can exhibit complex dynamics like oscillations using Watson-Crick base pairing alone, without relying on traditional enzymatic processes.

Scaling up DNA data storage and randomaccess retrieval

This paper demonstrates large-scale DNA data storage with random access, storing 200MB of data in 13 million DNA oligonucleotides and achieving error-free retrieval.