J. Richardson

Field evaluation of a volatile pyrethroid spatial repellent and etofenprox-treated clothing for outdoor protection against forest malaria vectors in Cambodia

This study evaluates volatile pyrethroid spatial repellents and etofenprox-treated clothing for reducing Anopheles landings in Cambodia, finding substantial protective efficacies and significant reductions in vectorial capacity.

Disrupting the interaction between AMBRA1 and DLC1 is a promising therapeutic strategy for neurodegeneration that prevents apoptosis while enhancing autophagy and mitophagy

The paper investigates AMBRA1 mutants to identify strategies that prevent apoptosis and enhance autophagy/mitophagy in neurodegeneration, finding that AMBRA1TAT, which disrupts DLC1 interaction, shows the most promise.

Tick-borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2

This study identifies a mechanism by which tick-borne flaviviruses inhibit interferon signaling by targeting TYK2 catalytic activity through their NS5 protein.

Social attention across development in common ravens and carrion crows

This study examines how social context influences object and food interactions in ravens and crows across development, finding context-dependent barrier use and age-related behavioral changes.

Integrated protein-protein interaction and RNA interference screens reveal novel restriction and dependency factors for a tick-borne flavivirus in its human host

The paper identifies novel host proteins interacting with TBEV and characterizes their role as dependency or restriction factors using PPI screens and RNAi.

The soybean rust pathogen Phakopsora pachyrhizi displays transposable element proliferation that correlates with broad host-range adaptation on legumes

This study sequenced three Phakopsora pachyrhizi genomes, revealing high transposable element content and its correlation with host-range adaptation in legumes.

The outer surface protease, SepM, is required for blp locus activation in three of the four most common pherotypes of Streptococcus pneumoniae.

The paper shows that the protease SepM is required for activation of three out of four BlpC pherotypes in Streptococcus pneumoniae, with the fourth type being SepM-independent due to its shorter length.

EGFR-MAPK adaptor proteins mediate the epithelial response to Candida albicans via the cytolytic peptide toxin, candidalysin

This study identifies EGFR-MAPK adaptor proteins that mediate epithelial responses to C. albicans via candidalysin, showing their role in ERK1/2 signaling and cytokine production.

Single-domain antibodies for targeting, detection and in vivo imaging of human CD4+ cells

This study develops single-domain antibodies to target and image human CD4+ cells in vivo, demonstrating their utility in immunotherapy monitoring.

MBNL1 and RBFOX1 co-regulate alternative splicing events transcriptome-wide through a conserved buffering mechanism

This study identifies a conserved buffering mechanism where MBNL1 and RBFOX1 co-regulate alternative splicing by overlapping RNA motifs, reducing the range of splicing outcomes.

A conserved cell division protein directly regulates FtsZ dynamics in filamentous and unicellular actinobacteria

This study identifies SepH as a conserved actinobacterial protein that directly regulates FtsZ dynamics, promoting Z-ring formation and cytokinesis in Streptomyces and Mycobacterium.

Pathological modeling of TBEV infection reveals differential innate immune responses in human neurons and astrocytes that correlate with their susceptibility to infection.

This study establishes an in vitro model of TBEV infection in human brain cells, revealing differential innate immune responses in neurons and astrocytes that correlate with their susceptibility to the virus.

The immunomodulatory effect of IrSPI, a tick salivary gland serine protease inhibitor involved in Ixodes ricinus tick feeding

This paper identifies IrSPI, a tick salivary serine protease inhibitor, and shows it modulates the host immune response by inhibiting CD4+ T cell proliferation and altering cytokine secretion.

The Odd One Out: Arabidopsis Reticulon 20 Has A Role In Lipid Biosynthesis

This study identifies Arabidopsis reticulon 20 as involved in lipid biosynthesis based on its unique ER localization and altered sterol composition in mutants.