Author

M. Forcato

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 5 Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

S. Bicciato· 4 shared L. Pezze· 2 shared Y. Ciribilli· 2 shared A. Bisio· 1 shared A. R. Goldman· 1 shared A. Savarino· 1 shared A. Singh· 1 shared B. Lucic· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

S. Bicciato

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ETV7 reduces inflammatory responses in breast cancer cells by repressing TNFR1/NF-kappaB axis

E. M. Meskyte, L. Pezze, M. Forcato, I. A. Bocci, A. Bisio, S. Bicciato, D. Baltriukiene, Y. Ciribilli

This study shows ETV7 reduces inflammation in breast cancer by suppressing TNFR1 and NF-kappaB signaling through direct gene repression and competition with STAT3.

Cell Death & Disease · Apr 12, 2023Peer-reviewedCancer Biology

Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress

I. L. Shytaj, F. A. Procopio, M. Tarek, I. Carlon-Andres, H.-Y. Tang, A. R. Goldman, M. Munshi, M. Forcato, K. Leskov, F. Ye, B. Lucic, N. Cruz, A. Singh, S. Bicciato, S. Padilla-Parra, , A. Savarino

The paper shows that glycolysis downregulation is a hallmark of HIV-1 latency and that targeting antioxidant pathways can reactivate latent HIV-1.

bioRxiv · Dec 30, 2020Immunology

EphB6 regulates TFEB-lysosomal pathway and survival of disseminated indolent breast cancer cells

M. Zangrossi, P. Chakravarty, P. Romani, C. D. H. Ratcliffe, S. Hooper, M. Dori, M. Forcato, S. Bicciato, S. Dupont, E. Sahai, M. MONTAGNER

This study identifies EphB6 as a regulator of the TFEB-lysosomal pathway and survival of disseminated indolent breast cancer cells in a foreign environment.

bioRxiv · Nov 10, 2020Cancer Biology

ETV7 regulates breast cancer stem-like cell plasticity by repressing IFN-response genes

L. Pezze, M. Forcato, S. Pontalti, K. A. Badowska, D. Rizzotto, I.-I. Skvortsova, S. Bicciato, Y. Ciribilli

This study shows ETV7 promotes breast cancer stem-like cell plasticity and resistance to chemotherapy and radiotherapy by repressing IFN-response genes, which may be reversible with IFN-β treatment.

bioRxiv · Sep 2, 2020Cancer Biology

FGFR2 fusion protein-driven mouse models of intrahepatic cholangiocarcinoma unveil a necessary role for Erk signaling

G. Cristinziano, M. Porru, D. Lamberti, S. Buglioni, F. Rollo, C. A. Amoreo, I. Manni, D. Giannarelli, C. Cristofoletti, G. Russo, M. J. Borad, G. L. Grazi, M. G. Diodoro, S. Giordano, M. Forcato, , O. Segatto

This paper develops FGFR2 fusion protein-driven mouse models of intrahepatic cholangiocarcinoma and shows that Erk signaling is essential for tumor growth, with double blockade of FF-Ras-Erk pathways improving therapeutic efficacy.

bioRxiv · May 20, 2020 · PreprintCancer Biology