M. J. Jackson

Lifelong dietary protein restriction accelerates skeletal muscle loss and reduces muscle fibre size by impairing proteostasis and mitochondrial homeostasis

Deletion of Sod1 in motor neurons exacerbates age-related changes in axons and NMJs associated with premature muscle atrophy in aging mice

This study shows that deleting Sod1 in motor neurons worsens age-related muscle atrophy and NMJ changes in old mice, but not in younger mice.