MicrobiologybioRxiv
Highly basic clusters in the HSV-1 nuclear egress complex drive membrane budding by inducing lipid ordering
M. K. Thorsen, A. Lai, M. W. Lee…·E. E. Heldwein
This study identifies how basic regions in the HSV-1 nuclear egress complex induce lipid ordering and negative curvature to drive membrane budding, with phosphorylation inhibiting this process.
DOI 10.1128/mbio.01548-21