M. Kamel

Polyamines regulate cell fate by altering the activity of histone-modifying enzymes

This study shows that polyamines regulate cell fate by altering chromatin structure through interactions with histone-modifying enzymes.

The fungal protein Jps1 facilitates unconventional protein secretion through a direct phosphoinositide interaction

This study identifies Jps1 as a key protein facilitating unconventional secretion in Ustilago maydis by interacting with phosphoinositides, revealing its structural and functional roles in Cts1 export.

Emergence of the Novel Infectious bursal disease viruse Variant in Vaccinated Poultry Flocks in Egypt

The paper reports the emergence of a novel IBDV variant in Egyptian poultry farms in 2023, causing subclinical infections and immunosuppression, with genetic features distinct from previous strains.

Adaptive capacity of a DNA polymerase clamp-loader ATPase complex

The paper shows that single point mutations can restore function to a defective DNA polymerase clamp-loader complex by compensating for reduced affinity between the clamp loader and the sliding clamp.

Novel intracellular phospholipase B from Pseudomonas aeruginosa with activity towards endogenous phospholipids affects biofilm assembly

This paper identifies a novel phospholipase B from Pseudomonas aeruginosa that affects biofilm assembly by degrading phospholipids and regulating oligomerization.

Unsaturated fatty acids augment protein transport via the SecA:SecYEG translocon

This study shows that unsaturated fatty acids enhance SecA:SecYEG-mediated protein transport by altering the membrane interface and promoting SecA binding.