Host-directed therapy with 2-Deoxy-D-glucose inhibits human rhinoviruses, endemic coronaviruses, and SARS-CoV-2
L. Wali, M. Karbiener, S. Chou…·A.-D. Gorki
This study shows 2-deoxy-D-glucose inhibits replication of rhinoviruses, endemic coronaviruses, and SARS-CoV-2 in epithelial cells by disrupting viral RNA synthesis and reducing viral load.