BiochemistrybioRxiv
The formation of intramolecular secondary structure brings mRNA ends in close proximity
W.-J. C. Lai, M. Kayedkhordeh, E. V. Cornell…·D. N. Ermolenko
The paper shows that mRNAs from various organisms, including humans, inherently fold into structures bringing their ends within 7 nm, regardless of length, except for specific unstructured sequences.
DOI 10.1038/s41467-018-06792-z