Author

M. Keegan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. L. Powell· 2 shared G. G. Rosenthal· 2 shared M. Schumer· 2 shared P. Andolfatto· 2 shared A. P. Diaz-Loyo· 1 shared C. Payne· 1 shared D. Blakkan· 1 shared D. E. Reich· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersEvolutionary Biology

D. L. Powell

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Author profile →

3 papers

Recent·Most cited

The genetic architecture of the sexually selected sword ornament and its evolution in hybrid populations

D. L. Powell, C. Payne, M. Keegan, S. M. Banerjee, R. Cui, P. Andolfatto, M. Schumer, G. G. Rosenthal

The paper investigates the genetic architecture of a sexually selected sword ornament in swordtail fish, identifying a major QTL and candidate genes, and finding evidence of selection against the trait in hybrid populations.

bioRxiv · Jul 23, 2020Evolutionary Biology

Natural hybridization reveals incompatible alleles that cause melanoma in swordtail fish

D. L. Powell, M. Garcia, M. Keegan, P. Reilly, K. Du, A. P. Diaz-Loyo, S. Banerjee, D. Blakkan, D. E. Reich, P. Andolfatto, G. G. Rosenthal, M. Schartl, M. Schumer

Using a combination of mapping approaches, we identify interacting genes that lead to melanoma in hybrids and characterize their effects in natural hybrid populations.

bioRxiv · Dec 12, 2019Evolutionary Biology

Gibbs Free Energy, a thermodynamic measure of protein-protein interactions, correlates with neurologic disability

M. Keegan, H. T. Siegelmann, E. A. Rietman, G. L. Klement

The paper correlates Gibbs free energy with neurologic disability in Alzheimer's, Parkinson's, MS, TBI, and epilepsy using RNA data and disability scores.

bioRxiv · Jan 22, 2019Biophysics