K. Du

Durable Antimicrobial Microstructure Surface (DAMS) Enabled by 3D-Printing and ZnO Nanoflowers

This study develops a durable antimicrobial surface (DAMS) using 3D-printed microstructures and ZnO nanoflowers, showing over 90% bacterial reduction after 12 hours and effectiveness after abrasion.

Complex structural variation and behavioral interactions underpin a balanced sexual mimicry polymorphism

The paper identifies a genetic basis for a sexual mimicry polymorphism in swordtail fish and links it to behavioral interactions that may maintain the polymorphism.

Population origin, body mass, and viral infections influence drone honey bee (Apis mellifera) heat tolerance

The paper investigates how body mass, viral infections, Africanization, and geographic origin affect heat tolerance in drone honey bees, finding that body size and origin significantly influence survival, while sperm heat tolerance is impacted by viral infections.

Genome evolution is surprisingly predictable after initial hybridization

The paper shows that local ancestry in hybrid swordtail fish populations is repeatable due to strong early selection, and this repeatability increases with deeper evolutionary divergence.

Micropillar enhanced FRET-CRISPR biosensor for nucleic acid detection

This study develops a FRET-CRISPR biosensor with micropillars for HPV 16 DNA detection, showing improved sensitivity and addressing microfluidic bubble issues.

Pneumatic Nano-Sieve for CRISPR-based Detection of Drug-resistant Bacteria

This paper introduces a nano-sieve device for MRSA purification and detection using CRISPR, achieving a 15x concentration factor and 100 CFU/mL LOD.

Extracting herbicide and antibiotic natural products from a plant-microbe interaction system

This study identifies a plant-microbe interaction system where a rhizosphere bacterium produces molecules with dual antibiotic and herbicide functions, offering insights into novel natural product discovery.

Superhydrophobic Rotation-Chip for Computer-Vision Identification of Drug-Resistant Bacteria

The paper introduces a microfluidic device called Rotation-Chip for detecting drug-resistant bacteria without external instruments, achieving high fluid transport efficiency and 100% computer vision accuracy.

Pneumatic Controlled Nano-Sieve for Efficient Capture and Release of Nanoparticles

The paper introduces a pneumatic nano-sieve device for capturing and releasing nanoparticles, demonstrating efficient capture with high flow rates and micro-grooves.

The Effects of CdSe/ZnS Quantum Dots on the Photosynthesis Rate of the Chlorella Vulgaris Beads

This study investigates how CdSe/ZnS quantum dots affect the photosynthesis rate of Chlorella vulgaris beads, showing concentration and time-dependent effects.

On-Demand Fully-Enclosed Superhydrophobic-Optofluidic Device Enabled by High Precision Microstereolithography

This paper introduces a fully-enclosed superhydrophobic optofluidic system with low optical loss, demonstrating its application for CRISPR-labeled quantum dot quantification.

Understanding the Dynamics of Fluid-Structure Interaction with an Air Deflected Microfluidic Chip (ADMC)

The paper couples a deformable microfluidic system with a fluidic dynamic model to study fluid-structure interaction in transient flow, showing the model predicts liquid displacement dynamics and identifies overshooting and oscillation phenomena relevant to dentine hypersensitivity.

Amplification-free detection of viral RNA by super resolution imaging-based CRISPR/Cas13a System

This paper develops a CRISPR/Cas13a system combined with super resolution imaging for direct, amplification-free viral RNA detection with improved sensitivity.

Understanding Microbeads Stacking in Deformable Nano-Sieve for Efficient Plasma Separation and Blood Cell Retrieval

This paper presents a deformable microfluidic device using microbeads to separate plasma and retrieve blood cells, supported by imaging and computational modeling.

Collagen induced inflammations

This paper describes a protocol for inducing collagen-induced arthritis (CIA) in mice using bovine collagen type II and Freund's adjuvants, and reports associated enteritis and arthritis outcomes.

A 180 My-old female-specific genome region in sturgeon reveals the oldest known vertebrate sex determining system with undifferentiated sex chromosomes

The paper identifies a 180 My-old female-specific genome region in sturgeon, revealing an ancient undifferentiated sex chromosome system with ZZ/ZW sex determination.

High contrast probe cleavage detection on porous silicon biosensors via quantum dot labeled DNA probes

The paper demonstrates a high-contrast probe cleavage detection method using porous silicon biosensors and quantum dot-labeled DNA probes, achieving a significant signal shift for nucleic acid cleavage detection.

Transcriptional Feedback Disruption Yields Escape-Resistant Antivirals

This paper develops feedback-circuit disruptors that inhibit viral replication and prevent resistance evolution in herpesviruses.

The developmental and genetic architecture of the sexually selected male ornament of swordtails

The paper identifies genes associated with sword development in swordtail fish by analyzing transcriptional profiles and genetic mapping.

Magnetic Bead-Quantum Dot (MB-Qdot) CRISPR Assay for Instrument-Free Viral DNA Detection

The paper develops an instrument-free CRISPR-based assay using magnetic beads and quantum dots to detect viral DNA with a detection limit of ~0.5 nM, demonstrated using African swine fever virus.

Integrated Micropillar Polydimethylsiloxane Accurate CRISPR Detection (IMPACT) System for Rapid Viral DNA Sensing

The paper develops an IMPACT system for rapid viral DNA detection using CRISPR, achieving sensitivity from 0.1 to 10 nM without fluorescent quenchers.

Single Chlamydomonas reinhardi (C. reinhardtii) cell separation from bacterial cells and auto-fluorescence tracking with a nano-sieve device

This paper develops a nano-sieve device for separating microalgae from bacteria and tracking single cells via auto-fluorescence.

Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells and protects against liver fibrosis

This study shows that inhibiting xCT/SLC7A11 induces ferroptosis in myofibroblastic hepatic stellate cells, reducing liver fibrosis without worsening liver injury.

Natural hybridization reveals incompatible alleles that cause melanoma in swordtail fish

Using a combination of mapping approaches, we identify interacting genes that lead to melanoma in hybrids and characterize their effects in natural hybrid populations.

High-throughput and all-solution phase African Swine Fever Virus (ASFV) detection using CRISPR-Cas12a and fluorescence based point-of-care system

This paper develops a CRISPR-Cas12a-based system for rapid, sensitive, and specific ASFV detection without nucleic acid amplification, achieving a detection limit of 100 fM.

Synergistic antifungal effect of amphotericin B-loaded PLGA nanoparticles based ultrasound against C. albicans biofilms

This study shows that combining amphotericin B-loaded PLGA nanoparticles with ultrasound significantly reduces C. albicans biofilm biomass and activity in vitro and in a rat model.