Tetherin restricts SARS-CoV-2 replication despite antagonistic effects of Spike and ORF7a
E. Hagelauer, R. Lotke, D. Kmiec, D. Hu, M. Hohner, S. Stopper, M. Layer, R. Nchioua, F. Kirchhoff, D. Sauter, M. Schindler
This study shows that SARS-CoV-2 S and ORF7a antagonize Tetherin, but Tetherin still restricts SARS-CoV-2 replication.
bioRxiv · Jul 28, 2023 · PreprintMicrobiology