Author

M. Leduc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

M. Le Gall· 2 shared A. Basseville· 1 shared A. Cammas· 1 shared A. Fetiveau· 1 shared A. Lombes· 1 shared B. Hernandez-Suarez· 1 shared B. Miotto· 1 shared C. Guette· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCancer Biology

M. Le Gall

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism

L. Dumas, S. Shin, Q. Rigaud, M. Cargnello, B. Hernandez-Suarez, P. Herviou, N. Saint-Laurent, M. Leduc, M. Le Gall, D. Monchaud, E. Dassi, A. Cammas, S. Millevoi

The paper shows RNA G-quadruplexes regulate mitochondrial function by modulating cytoplasmic mRNA translation of nuclear-encoded mitochondrial proteins, impacting energy metabolism and cancer cell proliferation.

bioRxiv · Jan 29, 2024 · PreprintCancer Biology

BCL-xL antagonizes the deleterious effects of KRAS on mitochondrial scaffolding

N. Belaid, A. Basseville, G. Andre-Gregoire, A. Fetiveau, L. Maillet, F. Guilloneau, M. Leduc, C. Guette, L. Desaubry, J. Gavard, F. Gautier, P. Juin

This study shows BCL-xL prevents KRAS from disrupting mitochondrial scaffolding by maintaining proximity to prohibitin 2 and preventing mitochondrial mass decrease.

bioRxiv · Apr 13, 2022 · PreprintCell Biology

USP9X deubiquitinase couples the pluripotency network and cell metabolism to regulate ESC differentiation potential

M. de Dieuleveult, M. Leduc, E. Salataj, C. Ransy, J. Dairou, K. Homma, M. Le Gall, P. Bossard, A. Lombes, F. Bouillaud, L. Ferry, P.-A. Defossez, J.-C. Cadoret, H. Ichijo, S. A. Wood, , B. Miotto

This study identifies USP9X as a regulator of ESC differentiation potential by linking pluripotency networks and metabolism.

bioRxiv · Jan 13, 2020 · PreprintCell Biology