Cancer BiologybioRxivPreprint
RNA G-quadruplex dynamic steers the crosstalk between protein synthesis and energy metabolism
L. Dumas, S. Shin, Q. Rigaud…·S. Millevoi
The paper shows RNA G-quadruplexes regulate mitochondrial function by modulating cytoplasmic mRNA translation of nuclear-encoded mitochondrial proteins, impacting energy metabolism and cancer cell proliferation.
DOI 10.1101/2024.01.29.577192