Author

M. Lupia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1

Frequent Co-Authors

N. Colombo· 3 shared U. Cavallaro· 3 shared C. E. Villa· 2 shared G. Testa· 2 shared P. Lo riso· 2 shared R. Luongo· 2 shared A. Garbi· 1 shared A. Jungmann· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersCancer Biology

N. Colombo

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3 papers

Recent·Most cited

Matrix Gla Protein acts as a driver of stemness and tumor initiation in ovarian cancer

V. Nieddu, V. Melocchi, C. Battistini, G. Franciosa, M. Lupia, C. Stellato, G. Bertalot, J. V. Olsen, N. Colombo, F. Bianchi, U. Cavallaro

This study identifies Matrix Gla Protein (MGP) as a driver of stemness and tumor initiation in ovarian cancer by promoting Hedgehog signaling and enhancing tumor-initiating capacity.

Cell Death & Disease · Mar 28, 2023Peer-reviewedCancer Biology

Single cell derived organoids capture the self-renewing subpopulations of metastatic ovarian cancer

T. Velletri, C. E. Villa, M. Lupia, P. Lo riso, R. Luongo, A. Lopez Tobon, M. De Simone, R. J. P. Bonnal, S. Minucci, S. Piccolo, N. Colombo, M. Pagani, U. Cavallaro, G. Testa

This study develops a method to grow single-cell derived ovarian cancer organoids from patient ascites, which retain key subpopulations and features of the original metastasis not seen in 2D cultures.

bioRxiv · Nov 30, 2018 · PreprintCancer Biology

A cell-of-origin epigenetic tracer reveals clinically distinct subtypes of high grade serous ovarian cancer

P. Lo Riso, C. E. Villa, G. Gasparoni, R. Luongo, A. Manfredi, A. Vingiani, A. Jungmann, A. Garbi, M. Lupia, P. Laise, V. Das, G. Pruneri, G. Viale, N. Colombo, U. Cavallaro, , G. Testa

This study identifies DNA methylation differences between fimbrial and ovarian surface epithelia to create an epigenetic tracer that stratifies high grade serous ovarian cancer into clinically distinct subtypes with prognostic significance.

bioRxiv · Nov 30, 2018Cancer Biology