Author

A. Jungmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:metabolism & bioenergetics· 2 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. J. Rose· 2 shared A. Y. Chan· 2 shared D. Kehr· 2 shared E. Gao· 2 shared H. A. Katus· 2 shared J. Birkenstock· 2 shared J. Ritterhoff· 2 shared K. Varadi· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPhysiology

A. J. Rose

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

S100A1ct: a synthetic peptide derived from human S100A1 protein improves cardiac contractile performance and survival in pre-clinical heart failure models

D. Kehr, J. Ritterhoff, M. Glaser, L. Jarosch, R. Salazar, K. Spaich, K. Varadi, J. Birkenstock, M. Egger, E. Gao, W. J. Koch, H. A. Katus, N. Frey, A. Jungmann, C. Busch, , P. Most

This paper develops a synthetic peptide S100A1ct that improves cardiac function and survival in heart failure models by enhancing Ca2+ cycling and targeting SERCA2a and RyR2.

bioRxiv · Mar 4, 2023Pharmacology & Toxicology

Cardiac-targeted rAAV5-S100A1 gene therapy protects against adverse remodeling and contractile dysfunction in post-ischemic hearts

D. Kehr, J. Salatzki, B. Krautz, K. Varadi, J. Birkenstock, P. Schlegel, E. Gao, W. J. Koch, J. Riffel, F. Andre, K. Peppel, H. A. Katus, N. Frey, M. Busch, H. Pfannkuche, , P. Most

This study demonstrates that cardiac-targeted rAAV5-S100A1 gene therapy reduces adverse remodeling and improves contractile function in post-ischemic hearts in pigs and mice.

bioRxiv · Mar 3, 2023 · PreprintPathology

An endocrine-hepato-muscular metabolic cycle links skeletal muscle atrophy and hyperglycemia in type 2 diabetes

J. G. Okun, P. M. Rusu, A. Y. Chan, Y. W. Yap, T. Sharkie, J. Schumacher, S. Hille, K. Schmidt, A. Zota, A. Jungmann, L. Maggi, Y. Lee, M. Blueher, S. Herzig, M. Heikenwaelder, , A. J. Rose

This study identifies an endocrine-hepato-muscular metabolic cycle linking hyperglycemia and skeletal muscle atrophy in type 2 diabetes through dysregulated alanine metabolism and ALT enzyme activity.

bioRxiv · May 25, 2020 · PreprintPhysiology

Restriction of essential amino acids dictates the systemic response to dietary protein dilution

Y. W. Yap, P. M. Rusu, A. Y. Chan, B. C. Fam, A. Jungmann, S. M. Solon-Biet, C. K. Barlow, D. J. Creek, C. Huang, R. B. Schittenhelm, B. Morgan, D. Schmoll, B. Kiens, M. D. Piper, M. Heikenwalder, , A. J. Rose

This study shows that restricting essential amino acids, not non-essential ones, drives systemic metabolic responses to dietary protein dilution and genetic amino acid transport loss.

bioRxiv · Nov 20, 2019 · PreprintPhysiology

A cell-of-origin epigenetic tracer reveals clinically distinct subtypes of high grade serous ovarian cancer

P. Lo Riso, C. E. Villa, G. Gasparoni, R. Luongo, A. Manfredi, A. Vingiani, A. Jungmann, A. Garbi, M. Lupia, P. Laise, V. Das, G. Pruneri, G. Viale, N. Colombo, U. Cavallaro, , G. Testa

This study identifies DNA methylation differences between fimbrial and ovarian surface epithelia to create an epigenetic tracer that stratifies high grade serous ovarian cancer into clinically distinct subtypes with prognostic significance.

bioRxiv · Nov 30, 2018Cancer Biology