Author

M. M. Steele

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. W. Lund· 3 shared H. du Bois· 2 shared T. A. Heim· 2 shared T. Mudianto· 2 shared C. Hill· 1 shared D. Murugan· 1 shared I. D. Dryg· 1 shared J. C. Nolz· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

A. W. Lund

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Author profile →

3 papers

Recent·Most cited

CXCR6 promotes dermal CD8+ T cell survival and transition to long-term tissue residence

T. A. Heim, O. Ibrahim, Z. Lin, M. M. Steele, T. Mudianto, A. W. Lund

This study shows CXCR6 supports dermal CD8+ T cell survival and transition to long-term tissue residence by enhancing metabolic adaptation and reducing apoptosis.

bioRxiv · Feb 14, 2023Immunology

T cell Egress via Lymphatic Vessels Limits the Intratumoral T cell Repertoire in Melanoma

M. M. Steele, I. D. Dryg, D. Murugan, J. Femel, H. du Bois, C. Hill, S. A. Leachman, Y. H. Chang, L. M. Coussens, A. W. Lund

The paper shows that T cell egress via lymphatic vessels limits intratumoral T cell diversity, and that CXCR4 inhibition enhances T cell retention and improves immunotherapy response.

bioRxiv · May 30, 2022 · PreprintImmunology

Infection-induced dermal lymphatic zippering restricts viral dissemination from skin and promotes anti-viral CD8+ T cell expansion.

M. J. Churchill, H. du Bois, T. A. Heim, T. Mudianto, M. M. Steele, J. C. Nolz, A. W. Lund

This study shows that vaccinia virus infection causes dermal lymphatic capillary zippering via VEGFR2, which limits viral spread and enhances CD8+ T cell responses.

bioRxiv · Aug 26, 2021Immunology