Sodium Thiosulfate acts as an H2S mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerization
D. Macabrey, A. Longchamp, M. Macarthur, M. Lambelet, S. Urfer, J.-M. Corpataux, S. Deglise, F. ALLAGNAT
This study shows sodium thiosulfate prevents intimal hyperplasia by acting as an H2S mimetic, inhibiting VSMC proliferation and migration through microtubule depolymerization.
bioRxiv · Sep 9, 2021 · PreprintPhysiology