Author

A. Longchamp

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 6 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

F. Allagnat· 4 shared D. Macabrey· 3 shared J.-M. Corpataux· 3 shared M. Lambelet· 3 shared S. Deglise· 3 shared C. K. Ozaki· 2 shared J. R. Mitchell· 2 shared M. R. MacArthur· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersPhysiology

F. Allagnat

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Sulfur Amino Acid Restriction Enhances Exercise Capacity in Mice by Boosting Fat Oxidation

C. G. Mann, M. R. MacArthur, J. Zhang, S. Gong, J. E. AbuSalim, C. J. Hunter, W. Lu, T. Agius, A. Longchamp, F. Allagnat, J. Rabinowitz, J. R. Mitchell, K. De Bock, S. J. Mitchell

SAAR improves exercise capacity in mice by enhancing fat oxidation and substrate availability through VEGF signaling and CD36-dependent fatty acid transport.

bioRxiv · Jun 27, 2024Physiology

Optimization of liver graft function using a poly-pharmacological drug cocktail CEPT in a simulated transplant model

A. Kharga, M. Mojoudi, H. Chen, M. S. Taggart, A. T. Dinicu, O. S. Ozgur, B. Uygun, M. Toner, S. Tessier, H. Yeh, J. F. Markmann, A. Longchamp, K. Uygun

This study evaluates the effect of the drug cocktail CEPT on liver graft function during simulated transplantation, finding improved cellular function and reduced apoptosis markers.

bioRxiv · Feb 2, 2024Bioengineering

Cystathionine gamma lyase overexpression enhances neovascularization through NAD-dependent mechanisms

K. Kiesworo, M. R. MacArthur, P. Kip, T. Agius, D. Macabrey, M. Lambelet, L. Hamard, C. K. Ozaki, J. R. Mitchell, S. Deglise, S. J. Mitchell, F. Allagnat, A. Longchamp

This study shows that overexpressing cystathionine gamma lyase (CGL) enhances neovascularization in ischemic muscle through NAD-dependent mechanisms by improving endothelial cell migration.

bioRxiv · Sep 6, 2022 · PreprintPhysiology

Hydrogen sulfide release via the ACE inhibitor Zofenopril prevents intimal hyperplasia in human vein segments and in a mouse model of carotid artery stenosis

D. Macabrey, C. Deslarzes-Dubuis, A. Longchamp, M. Lambelet, C. K. Ozaki, J.-M. Corpataux, F. ALLAGNAT, S. Deglise

This paper shows that Zofenopril, an ACE inhibitor that releases hydrogen sulfide, reduces intimal hyperplasia more effectively than other ACE inhibitors in both mice and human vein segments.

bioRxiv · Sep 13, 2021Physiology

Sodium Thiosulfate acts as an H2S mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerization

D. Macabrey, A. Longchamp, M. Macarthur, M. Lambelet, S. Urfer, J.-M. Corpataux, S. Deglise, F. ALLAGNAT

This study shows sodium thiosulfate prevents intimal hyperplasia by acting as an H2S mimetic, inhibiting VSMC proliferation and migration through microtubule depolymerization.

bioRxiv · Sep 9, 2021 · PreprintPhysiology

ATF-4 and hydrogen sulfide signalling mediate longevity from inhibition of translation or mTORC1

C. Statzer, J. Meng, R. Venz, M. Bland, S. Robida-Stubbs, K. Patel, D. Petrovic, R. Emsley, P. Liu, I. Morantte, C. Haynes, W. B. Mair, A. Longchamp, M. Filipovic, T. K. Blackwell, C. Y. Ewald

The paper shows that ATF-4 and hydrogen sulfide signaling mediate longevity from translation or mTORC1 inhibition in C. elegans.

bioRxiv · Nov 2, 2020 · PreprintPhysiology

Impact of an intra-abdominal cooling device during open kidney transplantation in pigs

A. Longchamp, R. P. H. Meier, N. Colucci, A. Balaphas, L. Orci, A. Nastasi, G. Longchamp, S. Moll, A. Klauser, M. Pascual, F. Lazeyras, J.-M. Corpataux, L. Bühler

This study tests an intra-abdominal cooling device during open kidney transplantation in pigs, finding it reduces second warm ischemia time and improves renal function.

bioRxiv · Mar 5, 2019Physiology