D. Macabrey

The hydrogen sulfide donor sodium thiosulfate limits inflammation but aggravate smooth muscle cells apoptosis and aneurysm progression in a mouse model of abdominal aortic aneurysm

This study shows that sodium thiosulfate (STS), a hydrogen sulfide donor, reduces inflammation but worsens abdominal aortic aneurysm (AAA) progression by promoting smooth muscle cell apoptosis and ECM breakdown in mice.

Cystathionine gamma lyase overexpression enhances neovascularization through NAD-dependent mechanisms

This study shows that overexpressing cystathionine gamma lyase (CGL) enhances neovascularization in ischemic muscle through NAD-dependent mechanisms by improving endothelial cell migration.

Hydrogen sulfide release via the ACE inhibitor Zofenopril prevents intimal hyperplasia in human vein segments and in a mouse model of carotid artery stenosis

This paper shows that Zofenopril, an ACE inhibitor that releases hydrogen sulfide, reduces intimal hyperplasia more effectively than other ACE inhibitors in both mice and human vein segments.

Sodium Thiosulfate acts as an H2S mimetic to prevent intimal hyperplasia via inhibition of tubulin polymerization

This study shows sodium thiosulfate prevents intimal hyperplasia by acting as an H2S mimetic, inhibiting VSMC proliferation and migration through microtubule depolymerization.