Cancer BiologybioRxivPreprint
Macrophages drive the earliest anti-tumoral response to BCG therapy by directly killing bladder cancer through TNF signaling
M. Martinez-Lopez, C. R. de Almeida, M. Fontes…·R. Fior
This study identifies macrophages as key drivers of BCG therapy's anti-tumoral effect through direct TNF-mediated cancer cell killing, independent of adaptive immunity.
DOI 10.1101/2024.01.05.574391