A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer
C. Mayoh, A. Gifford, R. Terry, L. M. Lau, M. Wong, P. Rao, T. Shai-Hee, F. Saletta, D.-A. Khuong-Quang, V. Qin, M. Mateos, D. Meyran, K. E. Miller, A. Yuksel, E. V. Mould, , P. G Ekert
The paper develops a 15-gene immune signature to identify T-cell infiltration in high-risk paediatric cancers, finding up to 31% of such cancers have infiltrating T-cells.
bioRxiv · Sep 16, 2022 · PreprintCancer Biology