J. S. Lewis

The paper presents the largest experimental dataset of Cerenkov-emitting isotopes measured using IVIS, providing normalized radiance values for 21 isotopes across various emissions.

This study demonstrates that SWIR imaging with pHLIP ICG enables sensitive tumor detection and resection under ambient lighting conditions in a preclinical breast cancer model.

This study shows that Cryptococcus neoformans can be expelled from murine bone marrow-derived dendritic cells via vomocytosis, similar to macrophages, and is inhibited by phagosome and actin-modifying drugs.

This paper identifies CAV1 as a biomarker for trastuzumab efficacy in HER2-positive gastric cancer and shows that statin use enhances antibody therapy response.

The paper shows that the E. coli DnaB helicase does not use ATP during DNA replication, with polymerase-driven nucleotide incorporation providing the energy instead.

This study develops tumor-specific antibodies for early detection of pancreatic cancer using PET imaging in mouse models, identifying two mAbs that bind to CEACAM6 variants in tumors.

This study shows adding cold PSMA-11 reduces salivary gland and kidney uptake of [177Lu]-PSMA-617 without affecting tumor uptake in mice.

A PARP1-targeted Auger radiotherapeutic shows translational potential for imaging and killing cancer cells, resulting in tumor delineation and prolonged survival in a glioblastoma model.

The paper introduces an R package for rapid population assessments using camera trap data, enabling occupancy modeling with Shiny applications to analyze density changes.

The paper shows how DNA polymerase stability and exchange dynamics in the yeast replisome are tuned by local concentrations, enabling efficient replication and adaptation to genomic challenges.

This study visualizes how the E. coli replisome recruits and recycles single-stranded DNA-binding protein using two mechanisms, showing their physiological relevance.

This study identifies a primase-induced conformational switch that enhances the stability of the bacterial replisome by strengthening the interaction between the polymerase holoenzyme and the replicative helicase.

The paper uses a modified Cas9 protein to create a programmable roadblock for studying DNA replication fork arrest in vitro and in vivo.

This study uses a fluorescent probe to track RecA dynamics in live E. coli, showing it is stored during normal metabolism and rapidly mobilizes to form SOS-signaling complexes upon DNA damage.

This paper trains a machine learning model to classify animal species in camera trap images, achieving high accuracy and providing an R package for ecological use.