Author

J. Egger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

A. Chow· 2 shared A. L. Creason· 2 shared A. Quintanal-Villalonga· 2 shared C. M. Rudin· 2 shared E. Demir· 2 shared F. Uddin· 2 shared G. B. Mills· 2 shared J. Goecks· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

A. Chow

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Author profile →

4 papers

Recent·Most cited

Longitudinal and multimodal auditing of tumor adaptation to CDK4/6 inhibitors in HR+ metastatic breast cancers

A. L. Creason, J. Egger, C. Watson, S. Sivagnanam, K. Chin, K. MacPherson, J.-R. Lin, Y.-A. Chen, B. E. Johnson, H. S. Feiler, D. Galipeau, N. E. Navin, E. Demir, Y. H. Chang, C. L. Corless, , J. Goecks

This study creates a multimodal tumor atlas to analyze how metastatic HR+ breast cancers adapt to CDK4/6 inhibitors, revealing mechanisms like mTORC1 activation and immune microenvironment changes.

bioRxiv · Sep 27, 2023 · PreprintCancer Biology

Ongoing Replication Stress Response and New Clonal T Cell Development Discriminate Between Liver and Lung Recurrence Sites and Patient Outcomes in Pancreatic Ductal Adenocarcinoma

J. M. Link, C. Pelz, P. J. Worth, S. Owen, D. Keith, E. M. Langer, A. Grossblatt-Wait, A. L. Creason, J. Egger, H. Holly, I. English, K. MacPherson, M. Tsuda, J. Goecks, E. Demir, , R. C. Sears

This study identifies transcriptomic and immune features distinguishing liver and lung metastatic sites in PDAC, linking replication stress response and T cell clonal development to patient outcomes.

bioRxiv · May 4, 2022 · PreprintCancer Biology

Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation

A. Quintanal-Villalonga, H. Taniguchi, M. A. Hasan, F. Meng, F. Uddin, M. Donoghue, H. H. Won, S. S. Chavan, J. M. Chan, M. Ciampricotti, A. Chow, M. Offin, J. C. Chang, J. Ray-Kirton, J. Egger, , T. Sen

The paper identifies molecular mechanisms of neuroendocrine transformation in lung cancer using multi-omic analysis of tumors and clinical samples.

bioRxiv · Dec 2, 2020 · PreprintCancer Biology

Single cell profiling reveals novel tumor and myeloid subpopulations in small cell lung cancer

J. M. Chan, A. Quintanal-Villalonga, V. Gao, Y. Xie, V. Allaj, O. Chaudhary, I. Masilionis, J. Egger, A. Chow, T. Walle, M. Mattar, D. V. Yarlagadda, J. L. Wang, F. Uddin, M. Offin, , C. M. Rudin

The paper profiles single-cell transcriptomes of SCLC subtypes to identify novel tumor and myeloid subpopulations and their associations with metastasis and immune microenvironment changes.

bioRxiv · Dec 1, 2020Cancer Biology