Assessing Mouse Kidney Parvovirus' Ability to Confound Research by Examining its Effects on Renally Excreted Chemotherapeutics and its Impact on Pathologic Endpoints in the Adenine Model of Chronic Kidney Disease
A. C. Ritter, R. J. Ricart Arbona, R. S. Livingston, S. Monette, N. S. Lipman
This study evaluates how MKPV affects the pharmacokinetics of chemotherapeutics and histopathologic outcomes in a chronic kidney disease model, finding minimal impact on drug excretion and serum biomarkers but significant histologic changes.
bioRxiv · Dec 9, 2022 · PreprintPathology