Author

M. Modesti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. De Cian· 1 shared A. Gilman· 1 shared A. K. L. Leung· 1 shared A. Korotkov· 1 shared A. Maslov· 1 shared A. Patel· 1 shared A. Williams· 1 shared C. B. Nelson· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. De Cian

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Author profile →

2 papers

Recent·Most cited

DNA repair and anti-cancer mechanisms in the longest-living mammal: the bowhead whale

D. Firsanov, M. Zacher, X. Tian, Y. Zhao, T. L. Sformo, G. Tombline, S. A. Biashad, A. Gilman, N. Hamilton, A. Patel, M. Straight, M. Lee, J. Y. Lu, E. Haseljic, A. Williams, , Gladyshev

This study investigates DNA repair mechanisms in bowhead whales, showing their high efficiency and accuracy in repairing DNA damage, which may explain their long lifespan without cancer.

bioRxiv · May 7, 2023 · PreprintCancer Biology

Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells

E. B. Garcin, S. Gon, R. Prakash, M. R. Sullivan, G. J. Brunette, A. De Cian, J.-P. Concordet, C. Giovannangeli, W. G. Dirks, S. Eberth, K. A. Bernstein, M. Jasin, M. Modesti

This study investigates the roles of RAD51 paralogs in DNA repair across different human cell types, finding essential differences in their functions and identifying potential implications for cancer therapy.

bioRxiv · Apr 15, 2019Cell Biology