M. Mora

Genome-wide analysis of DNA uptake across the outer membrane of naturally competent Haemophilus influenzae

The paper develops a computational model and experimental approach to map DNA uptake preferences in Haemophilus influenzae, showing uptake peaks at USS sequences and efficient self-DNA uptake in mixed environments.

Molecular fluctuations as a ruler of force-induced protein conformations

This study uses single molecule magnetic tweezers to analyze variance in protein end-to-end fluctuations under force, showing that compliance changes scale with contour length and align with the FJC model.

The International Space Station selects for microorganisms adapted to the extreme environment, but does not induce genomic and physiological changes relevant for human health

The study analyzes the microbial environment of the ISS, finding it similar to Earth's confined spaces, with microorganisms adapted to the extreme environment but not causing genomic changes relevant to human health.

Dead or Alive? Molecular life-dead distinction in human stool samples reveals significantly different composition of the microbial community

This study uses PMA treatment to distinguish live from dead microbes in human stool samples, showing that 100 M PMA effectively reduces signals from dead cells.

Exosomes and exosomal miRNAs from muscle-derived fibroblasts promote skeletal muscle fibrosis

This study shows that exosomes from DMD fibroblasts promote fibrosis by transferring miR-199a-5p, which reduces caveolin-1 and activates fibroblast-to-myofibroblast conversion.