PathologybioRxiv
Exosomes and exosomal miRNAs from muscle-derived fibroblasts promote skeletal muscle fibrosis
M. Mora, S. Zanotti, S. Gibertini…·R. Mantegazza
This study shows that exosomes from DMD fibroblasts promote fibrosis by transferring miR-199a-5p, which reduces caveolin-1 and activates fibroblast-to-myofibroblast conversion.