Author

L. Maggi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Approach:biophysical modeling· 1

Frequent Co-Authors

A. J. Rose· 1 shared A. Jungmann· 1 shared A. Nicolas-Arago· 1 shared A. Y. Chan· 1 shared A. Zota· 1 shared C. Bragato· 1 shared C. Introna· 1 shared C.-P. Kung· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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1 shared paperPhysiology

A. J. Rose

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Conserved Lysine in transmembrane helix 5 is key for the inner gating of the LAT transporter BasC

J. Fort, A. Nicolas-Arago, L. Maggi, M. Martinez-Molledo, D. Kapiki, N. Zijlstra, S. Bodoy, E. Pardon, J. Steyaert, O. Llorca, M. Orozco, T. Cordes, M. Palacin

This study identifies a conserved lysine in TM5 of BasC as critical for cytoplasmic gate dynamics, showing its role in gating transitions and modulation by substrates and mutations.

bioRxiv · Mar 26, 2024 · PreprintBiochemistry

An endocrine-hepato-muscular metabolic cycle links skeletal muscle atrophy and hyperglycemia in type 2 diabetes

J. G. Okun, P. M. Rusu, A. Y. Chan, Y. W. Yap, T. Sharkie, J. Schumacher, S. Hille, K. Schmidt, A. Zota, A. Jungmann, L. Maggi, Y. Lee, M. Blueher, S. Herzig, M. Heikenwaelder, , A. J. Rose

This study identifies an endocrine-hepato-muscular metabolic cycle linking hyperglycemia and skeletal muscle atrophy in type 2 diabetes through dysregulated alanine metabolism and ALT enzyme activity.

bioRxiv · May 25, 2020 · PreprintPhysiology

ADAR1 editing dependency in triple-negative breast cancer

C.-P. Kung, K. A. Cottrell, S. Ryu, E. R. Bramel, R. D. Kladney, E. A. Bross, L. Maggi, J. D. Weber

This study shows ADAR1 is essential for TNBC cell proliferation and tumorigenesis, with its loss reducing proliferation and being rescued by IFNAR1 reduction.

bioRxiv · Jan 31, 2020Cancer Biology

Exosomes and exosomal miRNAs from muscle-derived fibroblasts promote skeletal muscle fibrosis

M. Mora, S. Zanotti, S. Gibertini, F. Blasevich, C. Bragato, S. Saredi, C. Introna, P. Bernasconi, L. Maggi, R. Mantegazza

This study shows that exosomes from DMD fibroblasts promote fibrosis by transferring miR-199a-5p, which reduces caveolin-1 and activates fibroblast-to-myofibroblast conversion.

bioRxiv · Feb 19, 2018Pathology