Overactive STAT3 drives accumulation of disease-associated CD21low B cells
E. Masle-Farquhar, T. J. Peters, K. J. Jackson, M. Singh, C. S. Ma, D. Suan, G. Uzel, I. Chua, J. W. Leiding, K. Heiskanen, K. Preece, L. Kainulainen, M. O Sullivan, M. A. Cooper, M. R. Seppänen, , C. C. Goodnow
This study shows that overactive STAT3 leads to the accumulation of disease-associated CD21low B cells in both humans and mice.
bioRxiv · Dec 20, 2021 · PreprintImmunology