MicrobiologybioRxivPreprint
A single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication and pathogenesis in vivo
T. Y. Taha, R. K. Suryawanshi, I. P. Chen…·M. Ott
This study shows that mutating the SARS-CoV-2 NSP3 Mac1 domain reduces viral replication and pathogenesis in vivo.