Author

M. P. Walker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

S. E. Lindner· 4 shared A. M. Minns· 2 shared K. J. Hart· 2 shared A. G. Matera· 1 shared C. Marques-da-Silva· 1 shared D. E. Kyle· 1 shared E. N. Vrana· 1 shared I. D. Meier· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersMicrobiology

S. E. Lindner

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Direct type I Interferon signaling in hepatocytes control malaria

C. Marques-da-Silva, K. Peissig, M. P. Walker, J. Shiau, D. E. Kyle, R. Vijay, S. E. Lindner, S. P. Kurup

This study shows that direct type I interferon signaling in infected hepatocytes is necessary and sufficient to control malaria, revealing cell-autonomous immune responses.

bioRxiv · Jan 26, 2022Immunology

Extensive Transcriptional and Translational Regulation Occur During the Maturation of Malaria Parasite Sporozoites

S. E. Lindner, K. E. Swearingen, M. J. Shears, M. P. Walker, E. N. Vrana, K. J. Hart, A. M. Minns, P. Sinnis, R. L. Moritz, S. H. Kappe

This study identifies two waves of translational repression in malaria sporozoite maturation using transcriptomic and proteomic data from Plasmodium species.

bioRxiv · May 20, 2019 · PreprintMicrobiology

Ribozyme-Mediated, Multiplex CRISPR Gene Editing and CRISPRi in Plasmodium yoelii

M. P. Walker, S. E. Lindner

This paper develops CRISPR-RGR, a gene editing system for Plasmodium yoelii that enables marker-free, scar-free gene disruptions and insertions with high efficiency using ribozyme-flanked sgRNAs.

bioRxiv · Nov 29, 2018Microbiology

Plasmodium male gametocyte development and transmission are critically regulated by general and transmission-specific members of the CAF1/CCR4/NOT complex

K. J. Hart, J. Oberstaller, M. P. Walker, A. M. Minns, M. F. Kennedy, I. Padykula, J. Adams, S. E. Lindner

This study identifies PyCCR4-1 as a key regulator of male gametocyte development and transmission in Plasmodium, showing its role in mRNA stability and parasite infectivity.

bioRxiv · Jun 18, 2018Microbiology

Gemin4 is an essential gene in mice, and its overexpression in human cells causes relocalization of the SMN complex to the nucleoplasm

I. D. Meier, M. P. Walker, A. G. Matera

bioRxiv · Jan 4, 2018Cell Biology