Author

M. P. Weir

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

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Research Focus:protein folding & dynamics· 3 Organism:E. coli· 2 Approach:experimental assay· 2 Assay:structural biology· 2 Approach:biophysical modeling· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

D. Krizanc· 3 shared K. Scopino· 3 shared C. Dalgarno· 2 shared K. M. Thayer· 2 shared A. Elsayed· 1 shared C. Nachmannoff· 1 shared C. Nachmanoff· 1 shared E. Sakkas· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersBiophysics

D. Krizanc

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3 papers

Recent·Most cited

BiophysicsbioRxivJan 6, 2022

The CAR mRNA-Interaction Surface is a Zipper Extension of the Ribosome A Site

C. Dalgarno, K. Scopino, M. Raval…·M. P. Weir

The paper investigates the CAR-mRNA interaction surface, revealing its sequence specificity and role in translational regulation through molecular dynamics and nucleotide substitution experiments.

DOI 10.3390/ijms23031417

proteomicsmechanistic / dynamical model

𝕏 PostBluesky

BiophysicsbioRxivDec 21, 2020

Arginine Methylation Regulates Ribosome CAR Function

K. Scopino, C. Dalgarno, C. Nachmannoff…·M. P. Weir

This study shows that arginine methylation of ribosomal protein R146 reduces CAR interaction with the +1 codon, affecting translation regulation under stress.

DOI 10.3390/ijms22031335

E. coliyeast

𝕏 PostBluesky

BiophysicsbioRxivApr 28, 2020

A Ribosome Interaction Surface Sensitive to mRNA GCN Periodicity

K. Scopino, E. Williams, A. Elsayed…·M. P. Weir

The paper identifies a ribosome surface that interacts with mRNA GCN codons, showing sequence-specific hydrogen bonding that influences translation regulation.

DOI 10.3390/biom10060849

E. colistructural biology

𝕏 PostBluesky