Cancer BiologybioRxiv
Mast cells impair melanoma cell homing and metastasis by inhibiting HMGA1 secretion.
A. Benito-Martin, M. Hergueta-Redondo, L. Nogues…·H. Peinado
This study shows mast cells inhibit melanoma metastasis by reducing HMGA1 secretion, with HMGA1 expression linked to poorer survival in human melanoma.