Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for therapy
M. Karim, S. Saul, L. Ghita, M. K. Sahoo, C. Ye, N. Bhalla, J. Jin, J.-G. Park, B. Martinez-Gualda, M. Patrick East, G. L. Johnson, B. A. Pinsky, L. Martinez-Sobrido, C. R. M. Asquith, A. Narayanan, , S. Einav
This study shows that Numb-associated kinases are essential for SARS-CoV-2 infection and that inhibiting them can suppress viral infection in human lung cells.
bioRxiv · Mar 18, 2022 · PreprintMicrobiology