Author

S. Saul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Narayanan· 3 shared M. Karim· 3 shared N. Bhalla· 3 shared S. Einav· 3 shared B. A. Pinsky· 2 shared J. Jin· 2 shared L. Ghita· 2 shared S. De Jonghe· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersMicrobiology

A. Narayanan

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Author profile →

3 papers

Recent·Most cited

Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for therapy

M. Karim, S. Saul, L. Ghita, M. K. Sahoo, C. Ye, N. Bhalla, J. Jin, J.-G. Park, B. Martinez-Gualda, M. Patrick East, G. L. Johnson, B. A. Pinsky, L. Martinez-Sobrido, C. R. M. Asquith, A. Narayanan, , S. Einav

This study shows that Numb-associated kinases are essential for SARS-CoV-2 infection and that inhibiting them can suppress viral infection in human lung cells.

bioRxiv · Mar 18, 2022 · PreprintMicrobiology

Discovery of pan-ErbB inhibitors protecting from SARS-CoV-2 replication, inflammation, and lung injury by a drug repurposing screen

S. Saul, M. Karim, P.-T. Huang, L. Ghita, W. Chiu, S. Kumar, N. Bhalla, P. Leyssen, C. A. Cohen, K. E. Huie, C. Tindle, M. Sibai, B. A. Pinsky, S. Das, P. Ghosh, , S. Einav

This study identifies lapatinib, an ErbB inhibitor, as a broad-spectrum antiviral that suppresses SARS-CoV-2 and VEEV replication, inflammation, and lung injury through ErbB-mediated mechanisms.

bioRxiv · May 15, 2021Microbiology

The transcriptional landscape of Venezuelan equine encephalitis virus (TC-83) infection

Z. Yao, F. Zanini, S. Kumar, M. Karim, S. Saul, N. Bhalla, N. Panpradist, A. Muniz, A. Narayanan, S. R. Quake, S. Einav

This study uses single-cell RNA sequencing to analyze the host and viral RNA dynamics during VEEV infection, identifying superproducer cells and candidate antiviral targets.

bioRxiv · Feb 18, 2020Microbiology