Cell BiologybioRxiv
Pancreatic Beta Cell Autophagy is Impaired in Type 1 Diabetes
C. Muralidharan, A. M. Conteh, M. R. Marasco…·A. K. Linnemann
This study shows impaired autophagy in pancreatic beta cells of type 1 diabetes patients and a mouse model, with reduced autophagosome-lysosome colocalization and telolysosome accumulation.