Author

M. Rance

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Biophysics· 1

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

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D. J. Kojetin· 1 shared D. P. Marciano· 1 shared E. Matta-Camacho· 1 shared I. M. S. de Vera· 1 shared J. Shang· 1 shared P. K. Giri· 1 shared P. Munoz-Tello· 1 shared P. R. Griffin· 1 shared

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1 shared paperBiophysics

D. J. Kojetin

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1 paper

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BiophysicsbioRxivApr 17, 2018

Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1

I. M. S. de Vera, P. Munoz-Tello, V. Dharmarajan…·D. J. Kojetin

This study shows the Nurr1 ligand-binding domain has a dynamic, solvent-accessible pocket that can bind unsaturated fatty acids, challenging the notion that it lacks a canonical ligand-binding pocket.

DOI 10.1016/j.str.2018.10.002

structural biologymechanistic / dynamical model

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