Author

M. Roche

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Traversier· 2 shared B. Lina· 2 shared B. Padey· 2 shared C. Legras-Lachuer· 2 shared C. Nicolas de Lamballerie· 2 shared G. Boivin· 2 shared J. Textoris· 2 shared M. Rosa-Calatrava· 2 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. Traversier

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Airway basal stem cells are necessary for the maintenance of functional intraepithelial airway macrophages.

T. Kooistra, B. Saez, M. Roche, A. Egea-Zorrilla, D. Li, D. Anketell, N. Nguyen, J. Villoria, J. Gillis, E. Petri, L. Vera, N. P. Smith, J. Alladina, Y. Zhang, V. Vinarsky, , A. Pardo-Saganta

This study shows that airway basal stem cells maintain intraepithelial airway macrophages via Notch signaling, enabling localized allergic inflammation in the trachea but not distal lung tissues.

bioRxiv · Jun 25, 2024Cell Biology

Metabolic Dependency Shapes Bivalent Antiviral Response in Host Cells in response to poly:IC: The Role of Glutamine

G. Lebeau, A. Paulo-Ramos, M. Hoareau, D. El Safadi, O. Meilhac, P. Krejbich-Trotot, M. Roche, W. Viranaicken

This study shows that glutamine metabolism influences antiviral gene expression through oxidative phosphorylation and glycolytic pathways in response to poly:IC.

bioRxiv · Aug 31, 2023Immunology

Human Respiratory Syncytial Virus-induced immune signature of infection revealed by transcriptome analysis of clinical pediatric nasopharyngeal swab samples

C. Nicolas de Lamballerie, A. Pizzorno, J. Dubois, B. Padey, T. Julien, A. Traversier, J. Carbonneau, E. Orcel, B. Lina, M.-E. Hamelin, M. Roche, J. Textoris, G. Boivin, C. Legras-Lachuer, O. Terrier, M. Rosa-Calatrava

This study identifies an HRSV-induced immune signature in pediatric nasal wash samples using transcriptome analysis.

bioRxiv · May 20, 2020Microbiology

Repurposing of drugs as novel influenza inhibitors from clinical gene expression infection signatures

M. A. Pizzorno, O. Terrier, C. Nicolas de Lamballerie, T. Julien, B. Padey, A. Traversier, M. Roche, M.-E. Hamelin, C. Rheaume, S. Croze, V. Escuret, J. Poissy, B. Lina, C. Legras-Lachuer, J. Textoris, , M. Rosa-Calatrava

This paper identifies 35 FDA-approved drugs with antiviral potential against influenza using transcriptomic signatures, validates 31 in vitro, and highlights diltiazem as a promising candidate for Phase II clinical trials.

bioRxiv · Aug 27, 2018Microbiology