Author

W. Bakhache

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. B. McDermott· 1 shared B. Bonaventure· 1 shared C. Bories· 1 shared C. Goujon· 1 shared E. Partiot· 1 shared H. Xie· 1 shared I. Kosik· 1 shared J. D. S. Santos· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

A. B. McDermott

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Author profile →

2 papers

Recent·Most cited

C1q Enables Influenza HA Stem Binding Antibodies to Block Viral Attachment and Broadens the Antibody Escape Repertoire

I. Kosik, J. D. S. Santos, M. Angel, Z. Hu, J. Holly, J. S. Gibbs, T. U. Gill, M. Kosikova, T. Li, W. Bakhache, P. T. Dolan, H. Xie, S. F. Andrews, R. A. Gillespie, M. Kanekiyo, , j. yewdell

This study shows that C1q enhances anti-hemagglutinin stem antibody neutralization by blocking viral attachment and expanding the viral escape repertoire.

bioRxiv · Jun 12, 2023 · PreprintMicrobiology

Pharmacological perturbation of intracellular dynamics as a SARS-CoV-2 antiviral strategy

W. Bakhache, E. Partiot, V. Lucansky, Y. Bare, B. Bonaventure, C. Goujon, C. Bories, M. S. Deffieu, R. Gaudin

This paper identifies RG10 and RG10b as potent antiviral compounds against SARS-CoV-2 by perturbing ER/virus dynamics, with RG10b showing improved stability and efficacy.

bioRxiv · Sep 10, 2021 · PreprintMicrobiology