Targeting monocytic Occludin impairs monocyte transmigration and HIV neuroinvasion
D. Brychka, N. V. Ayala-Nunez, Y. Bare, A. Dupas, E. Partiot, V. Mittelheisser, V. Lucansky, J. G. Goetz, N. Osmani, R. Gaudin
This study shows that monocytic Occludin promotes monocyte transmigration into the CNS and that targeting it with peptides can block HIV neuroinvasion.
bioRxiv · Sep 11, 2023 · PreprintCell Biology